Selection.deleteFromDocument()

deleteFromDocument()

<p>Try highlighting some of the text in this paragraph. Once you do, you can remove the selected content by clicking the button below.</p>
<button>Delete selected text</button>

let button = document.querySelector('button');
button.addEventListener('click', deleteSelection);

function deleteSelection() {
  let selection = window.getSelection();
  selection.deleteFromDocument();
}